Volume No. :   1

Issue No. :  2

Year :  2009

ISSN Print :  0975-4393

ISSN Online :  2349-2988


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Recent Synthesis of Marine Natural Products with Anticancer Activity: An Overview



Address:   Nachiket S Dighe*1, Shashikant R Pattan1, Deepak S Musmade1, Abhijeet N Merekar2, Manisha S Kedar1, Deepak K Thakur1 and Pratik V Patel1
1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, 413736 (MS) India.
2Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, 413736 (MS) India.
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ABSTRACT:
Many natural products from marine sources are endowed with promising anti cancer activity, thus representing invaluable leads in the plans for drug discovery. In this context, organic synthesis plays a decisive role in confirming (or revising) the chemical structures of the natural compounds allowing also access to suitable amounts of the target (and its analogs) for structure activity relationship (SAR) investigations. In this overview, we focus on the total and partial synthesis of anti cancer marine metabolites and their related compounds discussing the retro synthetic analysis of the strategies adopted.
KEYWORDS:
Marine, Anti Cancer Activity, Synthesis of Dictyostatin.
Cite:
Nachiket S Dighe, Shashikant R Pattan, Deepak S Musmade, Abhijeet N Merekar, Manisha S Kedar, Deepak K Thakur, Pratik V Patel. Recent Synthesis of Marine Natural Products with Anticancer Activity: An Overview. Research J. Science and Tech. 2009; 1(2): 63-70 .
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