Volume No. :   3

Issue No. :  2

Year :  2011

ISSN Print :  0975-4393

ISSN Online :  2349-2988


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Mass Spectroscopy: A Versatile Analytical Technique



Address:   Dubey R.D.1*, Ahmad A.R.1, Paroha S.2, Gupta R.K.3, Sahu P. K.1, Verma S.1, Daharwal S. J.1 and Prasad Reddy S.L.N.4
1Institute of Pharmacy, RITEE, Chhatauna, Mandir Hasaud, Raipur, Chhattisgarh, India.
2Siddhi Vinayaka Institute of Technical Sciences, Mangla, Bilaspur, Chhattisgarh, India.
3J. K. College of Pharmacy, Gatora, Bilaspur, Chhattisgarh, India.
4Samskruti College of Pharmacy, Kondapur, Ghatkesar, RR Dist, Hyderabad, Andhra Pradesh, India.
*Corresponding Author
DOI No:

ABSTRACT:
Mass spectrometry (MS) is an analytical technique for the determination of the elemental composition of a sample or molecule. It is also used for elucidating the chemical structures of molecules, such as peptides and other chemical compounds. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measurement of their mass-to-charge ratios. There are different types of the Mass spectroscopy included in this review like AMS (Accelerator Mass Spectrometry), Gas Chromatography-MS, Liquid Chromatography-MS, ICP-MS (Inductively Coupled Plasma-Mass spectrometry), IRMS (Isotope Ratio Mass Spectrometry), Ion Mobility Spectrometry-MS, MALDI-TOF, SELDI-TOF, Tandem MS, TIMS (Thermal Ionization-Mass Spectrometry), SSMS (Spark Source Mass Spectrometry). The application of Mass spectroscopy are Isotope ratio MS: isotope dating and tracking, trace gas analysis, atom probe, pharmacokinetics, protein characterization, space exploration, respired gas monitor. In this review we try to describe the type, principle, methodology and application of Mass Spectroscopy.
KEYWORDS:
Mass spectroscopy, Analytical technique, Chemical structure, Chromatography.
Cite:
Dubey R.D., Ahmad A.R., Paroha S., Gupta R.K., Sahu P. K., Verma S., Daharwal S. J., Prasad Reddy S.L.N.. Mass Spectroscopy: A Versatile Analytical Technique. Research J. Science and Tech. 3(2): March-April. 2011: 55-64.
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