Volume No. :   4

Issue No. :  3

Year :  2012

ISSN Print :  0975-4393

ISSN Online :  2349-2988


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Screening of Antipyretic and Analgesic Potential of Ethanol Extract of Cassytha filiformis Leaves



Address:   Ram Kumar Sahu1*, Amit Roy1, SaurabhKothiya2, Anup Kumar Maurya3, Rajesh Kumar4
1Columbia Institute of Pharmacy, Tekari, Raipur (C.G.)-493111, India.
2Oriental College of Pharmacy, Raisen Road, Bhopal-462021 (M.P.), India.
3Shridhar University, Pilani-333031 (Rajasthan), India.
4Institute of Pharmacy, Kathog-177101 (H.P.), India
*Corresponding Author
DOI No:

ABSTRACT:
The present study was undertaken to evaluate the antipyretic and analgesic activities of the alcohol extract of Cassytha filiformis leaves. The antipyretic activity of C. filiformis (25mg/kg, 50mg/kg and 100mg/kg) was studied in Brewer’s yeast induced pyrexia in rats. The analgesic activity of C. filiformis (25mg/kg, 50mg/kg and 100mg/kg) was studied using Eddy’s hot plate method and heat conduction method in mice. The extract showed significant reduction in the elevated body temperature of rat which was compared with standard Paracetamol. The extract produced significant increase in the reaction time by Eddy”s hot plate method and tail flick method in mice which was compared with standard diclofenac sodium. The alcohol extract of leaves of C. filiformis may have antipyretic and analgesic activities.
KEYWORDS:
Cassytha filiformis, antipyretic, pyrexia, analgesic, paracetamol
Cite:
Ram Kumar Sahu, Amit Roy, SaurabhKothiya, Anup Kumar Maurya, Rajesh Kumar. Screening of Antipyretic and Analgesic Potential of Ethanol Extract of Cassytha filiformis Leaves. Research J. Science and Tech. 2012; 4(3): 129-131.
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