Volume No. :   12

Issue No. :  1

Year :  2020

ISSN Print :  0975-4393

ISSN Online :  2349-2988


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Formulation of Herbal Tablet with the help of Tulsi and Turmeric Extract which Showing Antimicrobial Activity



Address:   S. D. Mankar1*, Sahil B. Shaikh2, Avesh A. Tamboli2
1M.Pharm, Pharmaceutics, Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar. Rahata, Ahmednagar
2B.Pharm, Department of Pharmacy, Pravara Rural College of Pharmacy, Pravaranagar, Rahata, Ahmednagar
*Corresponding Author
DOI No: 10.5958/2349-2988.2020.00009.1

ABSTRACT:
This article reports the formulation and quality evaluations of tulsi tablets prepared for better applicability. Tulsi and turmeric extract combination herbal tablets were formulated by a combination of wet granulation and direct compression. Micrometric properties of the powder blend of herbal excipient was carried out prior to tablets compression followed by post compressional evaluation excipient mixed powder blend exhibited excellent flow properties. The formulations were stable enough as evident from the results of stability studies. The tablets prepared were satisfactory in terms of quality aspects and aided in better applicability of tulsi and turmeric extract. The aim is to formulation and to evaluation of the antimicrobial antifungal, antiulcarative effects showing of leaf and rhizomes extracts of O. sanctum against pathogenic bacteria to determine their potentials as antibacterial agent. Ocimum sanctum Linn and curcuma longa having family Lamiaceae and zingibariaceae simultaneously The family Lamiaceae is one of the most exploited medicinal plant family worldwide not only as a source of medicinal plants but also with its valuable essential oils being used as spices and flavours for various food products. Leaves have petioles, and are ovate, up to 5 cm long, usually slightly toothed. Leaves were separated from the stem, washed in clear water and dried until they were adequately dry to be ground (dried for 7 days). Dried leaves were powdered separately in an electric grinder until a homogenous powder was obtained and Ethanolic, Hexane, Chloroform extract was prepared from the powder. The extraction is done by using “cold extraction method. The activity of Tulsi extract against K. pneumonia and Staphylococcus aureus was found to be higher at a concentration of 100% followed by 75% and 50% respectively. The maximum zone of inhibition was found to be 18and15mm against Staphylococcus aureus. The antimicrobial efficacy of Ocimum sanctum leaves indicates that the plant possesses potent antimicrobial properties as well as Ocimum is widespread in India, it can be recommended as an easily available and renewal source of antimicrobial agent and wound healing agent instead of synthetic chemicals.
KEYWORDS:
Ocimum santum, Curcuma longa, Staphylococcus aureus, tablet.
Cite:
S. D. Mankar, Sahil B. Shaikh, Avesh A. Tamboli. Formulation of Herbal Tablet with the help of Tulsi and Turmeric Extract which Showing Antimicrobial Activity. Research J. Science and Tech. 2020; 12(1): 69-73.
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