Sonal Dubey, Sakshi Bhardwaj
Sonal Dubey1*, Sakshi Bhardwaj2
1College of Pharmaceutical Sciences, Dayananda Sagar University, Kumarswamy Layout, Bengaluru - 560078-India.
2Krupanidhi College of Pharmacy, Carmelaram Post, Varthur-Hobli Road, Bengaluru- 560035. India.
Volume - 14,
Issue - 4,
Year - 2022
N-(4-alkyl-4-oxo-1,3-thiazolidin-3-yl)-2-(5-nitro-1H-benzimidazole-1-yl)acetamide derivatives were designed and synthesis. Twelve novel derivatives were synthesized using conventional approach and Microwave-assisted synthesis. Herein we report the comparisonbetween the two approaches in terms of time, solvents used and yield. As evident from the results obtained the green chemistry approach for the synthesis is the more efficient way of synthesis in terms of time and yield. The synthesized compounds were subjected to anti tubercular Alamar Blue Assay. Some of them have shown promising activity.
Cite this article:
Sonal Dubey, Sakshi Bhardwaj. Synthesis of some Novel Benzimidazole-Oxothiazolidine Derivatives as Anti-Tubercular agents: Conventional Vs Microwave Assisted Approach. Research Journal of Science and Technology 2022; 14(4):199-7. doi: 10.52711/2349-2988.2022.00033
Sonal Dubey, Sakshi Bhardwaj. Synthesis of some Novel Benzimidazole-Oxothiazolidine Derivatives as Anti-Tubercular agents: Conventional Vs Microwave Assisted Approach. Research Journal of Science and Technology 2022; 14(4):199-7. doi: 10.52711/2349-2988.2022.00033 Available on: https://rjstonline.com/AbstractView.aspx?PID=2022-14-4-1
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