Author(s): Nikam Unnati Sahebrao, Nawale Sejal Navnath

Email(s): nawalesejal227@gmail.com

DOI: 10.52711/2349-2988.2024.00045   

Address: Nikam Unnati Sahebrao, Nawale Sejal Navnath
Pravara Rural College of Pharmacy, Pravaranagar. *Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2024


ABSTRACT:
The “wonder drugs” for fighting bacteria are antibiotics. Numerous antibiotic strains have been employed for many years not only as preventative measures but also as treatments in veterinary medicine and other fields including agriculture. There’s been uncertainty, since Common antibiotics have been rendered ineffective by microorganisms, and the host is oblivious to this development. By reviewing the literature, this review seeks to understand the causes, progression, and present-day aspects of antibiotic resistance as well as its regulatory framework and associated difficulties. Antibiotic resistance is growing at a startling rate, as we discovered. an expanding list Many diseases, including as gonorrhea, pneumonia, and tuberculosis, are getting tougher and occasionally impossible to treat while drugs are become less effective. The level of antibiotic intake and antibiotic-resistant illnesses are correlated. The majority of the resistance in microorganisms is caused by the non-medical usage of antibiotics. The range of antibiotics available to treat hard-to-treat, multidrug-resistant bacterial infections, whether they are new or emergent, is limited, leading to significant mortality and morbidity data report. In order to decrease antibiotic resistance, this review paper restates the best practices for using antimicrobial medications in both human and animal health. Research from the literature indicates that there is still a dearth of information about antibiotic resistance in the general public. Thus, it is crucial to educate the public and patients in order to combat the combat against antimicrobial resistance.


Cite this article:
Nikam Unnati Sahebrao, Nawale Sejal Navnath. A Review on Antibiotic Resistance: Alarm Bells are Ringing. Research Journal of Science and Technology. 2024; 16(4):313-6. doi: 10.52711/2349-2988.2024.00045

Cite(Electronic):
Nikam Unnati Sahebrao, Nawale Sejal Navnath. A Review on Antibiotic Resistance: Alarm Bells are Ringing. Research Journal of Science and Technology. 2024; 16(4):313-6. doi: 10.52711/2349-2988.2024.00045   Available on: https://rjstonline.com/AbstractView.aspx?PID=2024-16-4-7


REFERENCES:
1.    Levy SB, Marshall B: Antibacterial resistance worldwide: causes, challenges and responses. Nat Med. 2004, 10:122–129. 10.1038/nm1145
2.    Maranan MC, Moreira B, Boyle-Vavra S, et al.: Antimicrobial resistance in staphylococci: Epidemiology, molecular mechanisms, and clinical relevance. Infect Dis Clin North Am. 1997; 11: 813–849. 10.1016/S0891-5520(05)70392-5
3.    Levy SB: From tragedy the antibiotic age is born. The Antibiotic Paradox. Springer; 1992. 1–12.
4.    Aminov RI: A brief history of the antibiotic era: lessons learned and challenges for the future. Front Microbiol. 2010; 1: 134. 10.3389/fmicb.2010.00134
5.    Davies J, Davies D: Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev.2010, 74:417–433. 10.1128/MMBR.00016-10
6.    Chopra R, Alderborn G, Podczeck F, et al.: The influence of pellet shape and surface properties on the drug release from uncoated and coated pellets. Int J Pharm. 2002, 239:171–178. 10.1016/S0378-5173(02)00104-7
7.    Levy SB: The challenge of antibiotic resistance. Scientific American. 1998, 278:32–39.
8.    Grigoryan L, Burgerhof JG, Haaijer-Ruskamp FM, et al.: Is self-medication with antibiotics in Europe driven by prescribed use?. J Antimicrob Chemother. 2007, 59:152–156.10.1093/jac/dkl457
9.    Overview of Bacteria. (2017). Accessed: June 19:http://www.merckmanuals.com/home/infections/bacterial-infections/overview-of-bacteria.
10.    Levy SB: Antibiotic Resistance: An Ecological Imbalance, in Ciba Foundation Symposium 207- Antibiotic Resistance: Origins, Evolution, Selection and Spread. Chadwick DJ, Goode J. John Wiley & Sons, Ltd. (ed): Chichester, UK, 2007; 2007. 1:1-14. 10.1002/9780470515358.ch1
11.    Hoge CW, Gambel JM, Srijan A, et al.: Trends in antibiotic resistance among diarrheal pathogens isolated in Thailand over 15 years. Clin Infect Dis. 1998, 26:341–345.10.1086/516303
12.    Rahman AE, Iqbal A, Hoque DE, et al.: Managing neonatal and early childhood syndromic sepsis in sub-district hospitals in resource poor settings: improvement in quality of care through introduction of a package of interventions in rural Bangladesh. PloS one. 2017;12:10.1371/journal.pone.0170267
13.    Abraham EP, Chain E: An enzyme from bacteria able to destroy penicillin. Nature. 1940,146:837. 10.1038/146837a0
14.    Gootz TD: Discovery and development of new antimicrobial agents . Clin Microbiol Rev. 1990,3:13–31. 10.1128/CMR.3.1.13
15.    Jevons MP: “Celbenin”-resistant staphylococci. Br Med J. 1961, 1:124–125.
16.    Lowy FD: Antimicrobial resistance: the example of Staphylococcus aureus. J Clin Invest. 2003,111:1265–1273. 10.1172/JCI18535
17.    Appelbaum P: The emergence of vancomycin‐intermediate and vancomycin‐resistant Staphylococcus aureus. Clin Microbiol Infect. 2006, 12:16–23. 10.1111/j.1469-0691.2006.01344.x
18.    McEwen SA, Fedorka-Cray PJ: Antimicrobial use and resistance in animals. Clin Infect Dis.2002, 34:93–106. 10.1086/340246
19.    Witte W: Medical consequences of antibiotic use in agriculture. Science. 1998, 279:996–997.10.1126/science.279.5353.996
20.    Levy SB: The antimicrobial paradox. How miracle drugs are destroying the miracle. N Engl J Med. York, Plenum Press; 1993. 328:1792. 10.1056/NEJM199306173282418
21.    Garau J, Xercavins M, Rodríguez-Carballeira M, et al.: Emergence and dissemination of quinolone-resistant Escherichia coli in the community. Antimicrob Agents Chemother. 1999,43:2736–2741.
22.    Laxminarayan R, Brown GM: Economics of antibiotic resistance: A theory of optimal use. J Environ Econ Manage. 2001, 42:183–206. 10.1006/jeem.2000.1156
23.    Alanis AJ: Resistance to antibiotics: Are we in the post-antibiotic era? . Arch Med Res. 2005,36:697–705. 10.1016/j.arcmed.2005.06.009
24.    Goossens H, Ferech M, Vander Stichele R, et al.: Outpatient antibiotic use in Europe and association with resistance: A cross-national database study. The Lancet. 2005; 365: 579–587.
25.    Avorn J, Barrett JF, Davey PG, et al.: Antibiotic resistance: Synthesis of recommendations by expert policy. 2001,
26.    Chopra I, Roberts M: Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev. 2001, 65:232–260.10.1128/MMBR.65.2.232-260.2001
27.    Chadwick D, Goode J: Antibiotic resistance: origins, evolution, selection and spread. John Wiley, Sons; 1997.
28.    Lipp EK, Huq A, Colwell RR: Effects of global climate on infectious disease: The cholera model .Clin Microbiol Rev . 2002, 15:757–770. 10.1128/CMR.15.4.757-770.2002
29.    Fact sheet 2016- Antibiotic resistance. (2017). Accessed: 16 June:http://www.who.int/mediacentre/factsheets/antibiotic-resistance/en/..
30.    Aminov RI, Mackie RI: Evolution and ecology of antibiotic resistance genes. FEMS Microbial Lett. 2007, 271:147-161. 10.1111/j.1574-6968.2007.00757.x
31.    Freire-Moran L, Aronsson B, Manz C, et al.: Critical shortage of new antibiotics in development against multidrug-resistant bacteria—Time to react is now. Drug Resist Updat.2011, 14:118–124. 10.1016/j.drup.2011.02.003
32.    Anderson RM, May R: Infectious diseases of humans. Oxford. Publication Google, 1991.
33.    Perez Aldana L, Kato M, Nakagawa S, et al.: The relationship between consumption of antimicrobial agents and the prevalence of primary Helicobacter pylori resistance. Helicobacter. 2002, 7:306–309. 10.1046/j.1523-5378.2002.00096.x
34.    WHO: The treatment of diarrhea: a manual for physicians and other senior health workers. CAH. Geneva; 1995.
35.    Zaman SB, Hossain N, Yasir Arafat SM, et al.: Management of newborn infection: Knowledge and attitude among health care providers of selected sub-district hospitals in Bangladesh. IJPPH. 2017, 1:127–132.
36.    Zaman SB, Hossain N: Universal Health Coverage: A burning need for developing countries.

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