Author(s): Rajendra Jangde

Email(s): rjangdepy@gmail.com

DOI: Not Available

Address: Rajendra Jangde*
University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur (C.G.) 492010
*Corresponding Author

Published In:   Volume - 3,      Issue - 6,     Year - 2011


ABSTRACT:
Matrix metalloproteinases (MMP) are proteolytic enzymes that play an important role in various aspects of cancer progression. Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous Zn (++)-endopeptidases that collectively cleave most if not all of the constituents of the extracellular matrix. The present review discusses in detail the primary structures and the overlapping yet distinct substrate specificities of MMPs as well as the mode of activation of the unique MMP precursors. The regulation of MMP activity at the transcriptional level and at the extracellular level (precursor activation, inhibition of activated, mature enzymes) is also discussed. A final segment of the review details the current knowledge of the involvement of MMP in specific developmental or pathological conditions, including human periodontal diseases.


Cite this article:
Rajendra Jangde. Matrix metalloproteinase: An overview. Research J. Science and Tech. 2011; 3(6): 301-307 .


Recomonded Articles:

Author(s): A.K. Meena, Brijendra Singh, Uttam Niranjan, A.K. Yadav, A.K. Nagaria, Kiran, A. Gaurav, Vertika Gautam, R.Singh

DOI:         Access: Open Access Read More

Author(s): Anagha Bhaskaran, K. Pramod, K.C. Ajithkumar , U.S. Jijith

DOI: 10.5958/2349-2988.2016.00023.1         Access: Closed Access Read More

Author(s): Leena Sahu, Amit Roy, Trilochan Satapathy

DOI:         Access: Open Access Read More

Author(s): Tara Chand, Manoj Kr. Sharma, Fanish Kr. Pandey, Chaitali Chakraborty

DOI: 10.5958/2349-2988.2016.00017.6         Access: Open Access Read More

Author(s): Namrta Choudhary, M.B. Siddiqui , Shazia, K.M. Abdul Raoof

DOI:         Access: Open Access Read More

Author(s): Nachiket S Dighe, Shashikant R Pattan, Deepak S Musmade, Abhijeet N Merekar, Manisha S Kedar, Deepak K Thakur, Pratik V Patel

DOI:         Access: Open Access Read More

Author(s): NKD Devi, K Sujitha, BR Madhavi, BS Mrudula, MN Janaki, V Sri Ramya

DOI:         Access: Open Access Read More

Author(s): R. Balabhaskar, M. Hemalatha, U.S. Mahadeva Rao

DOI:         Access: Open Access Read More

Author(s): Ravi Natvarlal Patel, Urviben Yashodharbhai Patel , Dhrubo Jyoti Sen

DOI:         Access: Open Access Read More

Author(s): Dhrubo Jyoti Sen, Jimit S. Patel, Charoo S. Garg, Divyang H. Shah, Kiran M. Patel, Dhara S. Bhavsar, Tirtha V. Patel, Dhara M. Limbachia

DOI:         Access: Open Access Read More

Author(s): Sachin Aglawe, Amol Gayke, Prasad Murade, Prashant Swami, Pramod Game, Pratik Kadam, Shubham Kanawade, Yogesh Garud

DOI: 10.5958/2349-2988.2019.00040.8         Access: Closed Access Read More

Author(s): Amutha K., Rajagopal K., Senthil Kumaran B. , Karthikeyan S.

DOI:         Access: Open Access Read More

Author(s): Priyanka Pandey, Rakesh Mehta, Ravi Upadhyay

DOI:         Access: Open Access Read More

Author(s): B. Edwin Jose, P. Muralidharan

DOI: 10.5958/2349-2988.2019.00017.2         Access: Closed Access Read More

Research Journal of Science and Technology (RJST) is an international, peer-reviewed journal, devoted to science and technology...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2349-2988 


Recent Articles




Tags