Author(s):
Anuja Uddhav Deokar, Dr Suhas Siddheshwar, Sudarshan. B. Kakad
Email(s):
deokaranuja95@gmail.com
DOI:
10.5958/2349-2988.2020.00004.2 
Address:
Anuja Uddhav Deokar1*, Dr Suhas Siddheshwar2, Sudarshan. B. Kakad3
1Research Scholar, M Pharmacy, Pravara Rural College of Pharmacy, Pravaranagar
2Assistant Professor, Pravara Rural College of Pharmacy, Pravaranagar
3Assistant Professor, Pravara Rural College of Pharmacy, Pravaranagar
*Corresponding Author
Published In:
Volume - 12,
Issue - 1,
Year - 2020
ABSTRACT:
Rivaroxaban is oxazolidine derivatives having anticoagulant activity. In literature few analytical methods are discussed for the estimation of Rivaroxaban. The objective of this study is to develop and validate RP-HPLC method for the qualitative estimation of the drug. In most of the methods, the isocratic elution was carried out by using Acetonitrile, water and buffer as a mobile phase. The wavelength was in between 245 to 252 nm. The flow rate was approximately 1.0 ml/min. the temperature set was ambient temperature. The developed methods were validated as per ICH guidelines and this methods were found to be specific, precise, sensitive and robustness.
Cite this article:
Anuja Uddhav Deokar, Dr Suhas Siddheshwar, Sudarshan. B. Kakad. Analytical Method Development and Validation of Rivaroxaban- A Review. Research J. Science and Tech. 2020; 12(1):36-46. doi: 10.5958/2349-2988.2020.00004.2
Cite(Electronic):
Anuja Uddhav Deokar, Dr Suhas Siddheshwar, Sudarshan. B. Kakad. Analytical Method Development and Validation of Rivaroxaban- A Review. Research J. Science and Tech. 2020; 12(1):36-46. doi: 10.5958/2349-2988.2020.00004.2 Available on: https://rjstonline.com/AbstractView.aspx?PID=2020-12-1-4