ABSTRACT:
The microencapsulation is a technique which is modern and widely used in the pharmaceutical industries foe different purposes. For the reduction of cost, to increase the stability of product, to mask unpleasant tastes, and to improve the release properties of drug in pharmaceutical industries this type of technique is generally used. The objective of this paper is to study the different techniques of microencapsulation of pharmaceutical ingredients by different processes. Microencapsulation is a rapidly expanding technology. In this process of form relatively thin coatings to tiny particles of solids or droplets of liquids and dispersions. The different types of microcapsules and microspheres are form from a wide range of wall materials like monomers and polymers. By the help of physicochemical properties of the core, the wall composition and the microencapsulation technique used, different types of particles can be obtained. It is economic feasibility of large-scale production, including operating and other miscellaneous things, such as transportation cost, regulatory cost. Microencapsulation often contain a basic understanding of the general properties of microcapsules, that is nature of the core and coating materials, the stability and release property of the coated materials and the microencapsulation methods. By mechanical method microencapsulation has been in the addition of oily medicines to tableted dosage forms. This has been used to avoid problems inherent in producing tablets from otherwise tacky granulations. This was accomplished through improved flow properties. Significances of is method, For Sustained or prolonged drug release formulation, For Masking test and odor of many drugs. For converting liquid into free flowing properties, drugs which are sensitive to Light, oxygen, moisture they are easily convert to stable form. Microencapsulation technologies are applied in any area of the industry for formulation.
Cite this article:
S. D. Mankar, Sahil B. Shaikh. Microencapsulation: is an advance Technique of Drug formulation for Novel Drug Delivery System. Research J. Science and Tech. 2020; 12(3):201-210. doi: 10.5958/2349-2988.2020.00028.5
Cite(Electronic):
S. D. Mankar, Sahil B. Shaikh. Microencapsulation: is an advance Technique of Drug formulation for Novel Drug Delivery System. Research J. Science and Tech. 2020; 12(3):201-210. doi: 10.5958/2349-2988.2020.00028.5 Available on: https://rjstonline.com/AbstractView.aspx?PID=2020-12-3-6
REFERENCES:
1. Methavee Peanparkdee, Satoshi Iwamotoa, Ryo Yamauchi, 2016. Microencapsulation: A review of applications in the food and pharmaceutical industries. Reviews in Agricultural Science, Volume 4, page no.56.
2. A Poshadri and Aparna Kuna 2010. Microencapsulation Technology: A review. J.Res. Angrau, 38(1)86-102, Page no 86.
3. Sanjay Kumar Das, Sheba Rani Nakka David, Rajan Rajabalaya, 2011. Microencapsulation technique and its partial. In. J. Pharma Sic Tech, Volume 6, Page no 1.
4. Loveleen Preet Kaur, Sheenam Sharma, Tarun Kumar Guleri, 2013. Microencapsulation: A new era in novel drug delivery. International Journal of Pharmaceutical Research and Bio Science, Volume 2.
5. K.P. Sampath Kumar, Tejbe. Sk, Shameem Banu, P. Naga Lakshmi, D. Bhowmik, 2013 Microencapsulation Technology; Indian Journal of Research in Pharmacy and Biotechnology, Volume 1 Page 324.
6. Talat Farheen, Azmat Shaikh, Sadhana Shahi, 2017. A Review on a Process: Microencapsulation. International Journal of Pharma Research and Health Sciences, volume 5, page no 1823.
7. N. Venkata Naga Jyothi, P. Muthu Prasanna, Suhas Narayan Sakarkar, K. Surya Prabha,2010. Microencapsulation techniques, factors influencing encapsulation efficiency. Journal of Microencapsulation, volume 27(3), page no 87.
8. S.K. Gupta, I.J. Singhvi, M.K. Shirsat, G. Karwani, A. Agarwal, Aditi, 2011. Microencapsulation techniques and its application in pharmaceutical field. Asian Journal of Pharmaceutical Sciences and Clinical Research; Volume 1, page no 67.
9. Pablo Teixeira da Silva I, Leadir Lucy Martins Fries I, Cristiano Ragagnin de MenezesI,2014. Microencapsulation: concepts, mechanisms, methods and some applications in food technology; Ciência Rural, Santa Maria, volume 44, page no 1304.
10. P. Venkatesan, R. Manavalan and K. Valliappan,2009. Microencapsulation: a vital technique in novel drug delivery system. Journal of Pharmaceutical Science and Research; Volume 1, page no 26.
11. Ying Lu, Kinam Park, 2012. Microencapsulation: Methods and Pharmaceutical Applications. Encyclopedia of Pharmaceutical Science and Technology, Volume1 page no 1.
12. O’Donnell PB, Mc Ginity JW, 1997. Preparation of microspheres by solvent evaporation technique. Advanced Drug Delivery Reviews. V0lume 4, page no 25-42.
13. Hashidzume A, Ohara T, Morishima Y, 2002. Coacervation of hydrophobically modified polyanions by association with nonionic surfactants in water. Langmuir.
14. Ramington GA, 2006. The Science and Practice of Pharmacy. BI Publication, Volume 1, page no 924.
15. Lachman LA, Liberman HA, Kanig JL. The Theory and Practice of Industrial Pharmacy. Mumbai, India: Varghese Publishing House;3:414-415.
16. Ramington GA. The Science and Practice of Pharmacy. Delhi, India: BI Publication; 2006, 21st Edition, Volume I, Page no 924.
17. Leon L, Herbert AL, Joseph LK. Theory and practice of industrial pharmacy, Varghese Publishing House, 3rd Edition, 1990: 412-429. 18. Herman N. Microencapsulation techniques Applications and Problems, Journal of the Society of Cosmetic Chemists, Page no.85-98.
18. Rodrigues, R.A.F and Grosso, C.R.F, 2008. Cashew gum microencapsulation protects the aroma of coffee extracts. Journal of Microencapsulation, Volume 25, page no 13–20.
19. Schlameus, W. 1995. Centrifugal extrusion encapsulation: Encapsulation and Controlled Release of Food Ingredients. Risch, S.J.; Reineccius, American Chemical Society: Washington, DC, 1995.
20. Indian Pharmacopoeia, 3rd Ed. Delhi: Controller of Publications, 1996, vol. II, p A7.
21. Lulwah Y. Al-Furaih, Ibtisam M. Ababutain, Azzat B. Abd-El-Khalek, Ahmed M. Abdel-Salam, 2016. Effect of different microencapsulation materials on stability of Lactobacillus plantarum DSM 20174. African Journal of Biotechnology, Volume 15, Page no 1207.