ABSTRACT:
Due to the unique architecture and physiology of the eye, drug delivery scientists and pharmacologists have faced significant difficulties. Blood aqueous and blood-retinal barriers are examples of static barriers. Choroidal and dynamic barriers are examples of delivery of a medication alone or in a dose form is significantly hampered by conjunctival blood flow, lymphatic clearance, tear dilution, and efflux pumps, especially to the posterior segment. The study of influx transporters on various ocular tissues and the development of parent drug delivery strategies that target specific transporters have gained traction in recent years. To get beyond various static and dynamic obstacles, colloidal dosage forms such nanoparticles, Nano micelles, liposomes, and micro emulsions have been extensively researched. Novel Drug delivery strategies such as bio adhesive gels and fibrin sealant-based approaches were Developed to sustain drug levels at the target site. Designing non-invasive sustained drug delivery Systems and exploring the feasibility of topical application to deliver drugs to the posterior Segment may drastically improve drug delivery in the years to come. Current developments in the field of ophthalmic drug delivery promise a significant improvement in overcoming the Challenges posed by various anterior and posterior segment diseases.
Cite this article:
Aarti R. Sanap. A Review on Ophthalmic Drug Delivery System. Research Journal of Science and Technology. 2024; 16(1):79-6. doi: 10.52711/2349-2988.2024.00013
Cite(Electronic):
Aarti R. Sanap. A Review on Ophthalmic Drug Delivery System. Research Journal of Science and Technology. 2024; 16(1):79-6. doi: 10.52711/2349-2988.2024.00013 Available on: https://rjstonline.com/AbstractView.aspx?PID=2024-16-1-13
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