Author(s):
Hiranshi Arunbhai Patel, Anuradha Prajapati, Sachin Narkhede, Shailesh Luhar
Email(s):
helupatel0101@gmail.com , anupatel03@gmail.com , sachinnarkhedein@gmail.com , sv_pharma2008@yahoo.com
DOI:
10.52711/2349-2988.2025.00008
Address:
Hiranshi Arunbhai Patel¹*, Anuradha Prajapati, Sachin Narkhede, Shailesh Luhar
Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,
Gujarat Technological University, Salvav, Vapi, Gujarat, India 39619.
*Corresponding Author
Published In:
Volume - 17,
Issue - 1,
Year - 2025
ABSTRACT:
Stem cell-based treatments stand for a revolutionary planning in medicine, leveraging the inherent regenerative capabilities inside stem cells to heal damaged tissues and organs. Recent advancements in this area have significantly progressed, particularly with the introduction of induced Cellular stem cells (MSCs) and stem cells that are pluripotent (iPSCs). iPSCs, which are generated from adult somatic cells, provide opportunities for personalized therapies, while MSCs have demonstrated effectiveness in treating a variety of conditions, such as illness caused by graft-versus-host and osteoarthritis. Clinical applications have seen impressive results, notably in regenerative medicine, where stem cells have been utilized to repair heart tissue following myocardial infarctions and to foster neuroregeneration in spinal cord injuries. Despite these successes, challenges persist, such as concerns regarding tumor formation, ethical dilemmas, and the intricate nature of stem cell behavior within the body. Looking to the future, innovative technologies like gene editing, particularly CRISPR-Cas9, show promise for rectifying genetic defects in stem cells, which could lead to potential cures for genetic disorders. Moreover, advancements in 3D bioprinting and tissue engineering are working toward the development of functional organoids for transplantation, helping to alleviate the severe lack of available donor organs. In summary, stem cell-based therapies have the potential to transform medical treatment. To completely realize the amazing potential of stem cells in modern medicine and overcome current obstacles, researchers, physicians, and regulatory agencies must work together and conduct ongoing studies.
Cite this article:
Hiranshi Arunbhai Patel, Anuradha Prajapati, Sachin Narkhede, Shailesh Luhar. Stem Cell-Based Therapies: Progress and Promise in Medical Treatment. Research Journal of Science and Technology. 2025; 17(1):59-5. doi: 10.52711/2349-2988.2025.00008
Cite(Electronic):
Hiranshi Arunbhai Patel, Anuradha Prajapati, Sachin Narkhede, Shailesh Luhar. Stem Cell-Based Therapies: Progress and Promise in Medical Treatment. Research Journal of Science and Technology. 2025; 17(1):59-5. doi: 10.52711/2349-2988.2025.00008 Available on: https://rjstonline.com/AbstractView.aspx?PID=2025-17-1-8
REFERENCES:
1. Radhika G, Sreelakshmi Divya P, Prashanth Reddy G, Venkatesh P, Ravindra Reddy K. An Overview on Regenerative Medicine. Research J. Pharm. and Tech. 2010; 3(3): 727-728.
2. Diksha, Sazal Patyar. Role of Stem Cells in treatment of different Diseases. Research J. Pharm. and Tech. 2018; 11(8): 3667-3678.
3. Chris Noel Timothy, Samyuktha. P.S., M.P. Brundha. Dental pulp Stem Cells in Regenerative Medicine – A Literature Review. Research J. Pharm. and Tech. 2019; 12(8): 4052-4056.
4. Anjali Athanerey, Neha Rani Verma, Piyush Bhargava, P K Patra, Awanish Kumar. Mesenchymal stem cells prove a significant role in Chronic non-healing ulcer progressive healing. Research J. Pharm. and Tech. 2021; 14(1): 373-377.
5. S. Tamil Selvi. Stem Cell Therapy. Int. J. Adv. Nur. Management. 2017; 5(4): 361-364.
6. Muhammad Riza Hafidz Bahtiar, Amelia Aisyiah Anwar, Fitrul Azmi Eka Farhana, Shelsabilla Prameswari, Elly Munadziroh. An insight of Osthole, Bone marrow mesenchymal stem cells, and BMP-9 loaded carbon-based scaffolds as a Biomaterial candidate in Osteoporosis Therapy: A Narrative Review. Research Journal of Pharmacy and Technology. 2023; 16(1): 459-4
7. G. L. Abisha Bel. Effectiveness of the Structures Teaching Programme on Stem Cell Therapy. Int. J. of Advances in Nur. Management. 2020; 8(1):07-08.
8. Ganesh G. Dhakad, Bhagyashri O. Fate, Amruta R. Pandav, Abhijit V. Shrirao, N. I. Kochar, A. V. Chandewar. Review on Stem Cell Therapy and its Various Aspects. Research Journal of Pharmacology and Pharmacodynamics. 2023; 15(2): 77-6.
9. Kunal D. Sutar, Rutika D. Harshad, Omkar S. Sangar, Aishwarya C. Patil, Santosh A. Payghan. An Overview of Stem Cell Therapy. Research Journal of Topical and Cosmetic Sciences. 2022; 13(1): 21-6.
10. Abhijit Ray. Scope of Embryonic Stem Cells in research. Asian J. Nur. Edu. and Research. 2012; 2(2): 51-54.
11. Zhao, T., and Zhang, Z. The role of stem cells in wound healing. Regenerative Medicine. 2016; 11(1): 47-58. doi:10.2217/rme.15.50
12. Wong, M. T., and Wong, H. C. Ethical considerations in stem cell research: A review. Stem Cell Reports. 2020; 15(2): 272-281. doi: 10.1016/j.stemcr.2020.07.003
13. Kondo, Y., and Oka, Y. Current status of stem cell therapy for solid tumors. Cancer Science. 2018; 109(1): 18-24. doi:10.1111/cas.13410
14. Nussbaum, J. C., and Lang, J. E. Advances in 3D bioprinting for regenerative medicine. Nature Biotechnology. 2020; 38(3): 314-322. doi:10.1038/s41587-020-0466-0
15. Zhao, Y., and Wang, L. Gene editing and its application in stem cell therapy. Cell Stem Cell. 2019; 25(6): 901-914. doi: 10.1016/j.stem.2019.11.012