Quantum Dots (QDs) are semiconductor nanocrystals, which arose a new class for chemical analysis, molecular imaging, and biomedical diagnostics as fluorescent labels. There are traditional ways to synthesize QD. In QD micelle formation takes place, with hydrophobic tails and hydrophilic head. The core and the ligand play a key role in defining the properties of quantum dots. Colloidal Synthesis, Plasma Synthesis and Green Synthesis methods are followed to synthesize QD. The green synthesis method would be helpful in near future because of the use of oil and micro-organisms as raw material. In this paper, the size, shape of the QD, presence of ligand and other factors affecting the properties of QDs are discussed. Also, the toxic effects in vitro and in vivo imaging of QDs are highlighted along with the preventive measures to subjugate the difficulty. QDs overcome the limitations of organic dyes and fluorescent protein because of their ability to tune the size of fluorescence emission and generating any specific wavelength from UV through near infrared. QDs may provide the new class of biological values that can overcome the limitations of organic dyes and fluorescent protein. These properties are apposite for imaging and for multiplexed biomedical diagnostics at very high sensitivity. Hence, QDs are growing interest in medical field as an imaging tool of diseased tissues and organs.
Cite this article:
Dipti Bhave, Snehal Deshpande, Upendra Dabholkar. Surfactants as Quantum Dots used in Bio-Imaging.Research J. Science and Tech. 2018; 10(3):188-196. doi: 10.5958/2349-2988.2018.00026.8