Author(s): Njoku, Obioma U., Joshua, Parker Elijah, Okonkwo, Chukwudi C.

Email(s): ccokonkwo2008@yahoo.com

DOI: Not Available

Address: *Njoku, Obioma U., Joshua, Parker Elijah and Okonkwo and Chukwudi C.
Lipid and Lipoprotein Research Unit, Department of Biochemistry, University of Nigeria, Nsukka, Enugu, Nigeria
*Corresponding Author

Published In:   Volume - 3,      Issue - 4,     Year - 2011


ABSTRACT:
Gongronema latifolia (Utazi) is a plant found in the tropical regions of West Africa. The phytochemical analysis and the antioxidant activities of Gongronema latifolia were investigated. The acute toxicity of the plant was found to be 2450mg/kg body weight, indicating that the plant is safe for consumption. The ethanol extract of the plant gave a yield of 17.94%. The phytochemical analysis on the leaves extract revealed the presence of saponins, tannins, resins, carbohydrates, proteins, fats and oils, steroids, and terpenoids with higher levels of flavonoids and alkaloids. The antioxidant properties of ethanol extract of the plant were evaluated in vitro with rat liver homogenate. The ethanol extract of the plant showed a significant inhibition with nitric oxide, ferrous sulphate and carbon tetrachloride induced lipid peroxidation activities which were comparable with ascorbic acid. The inhibition was found to be concentration dependent. From this study, it was found that the plant is a potent scavenger of free radicals and can ameliorate the effects of oxidative stress which have been implicated in most pathological conditions.


Cite this article:
Njoku, Obioma U., Joshua, Parker Elijah, Okonkwo, Chukwudi C. Antioxidant Properties of Gongronema latifolia. Research J. Science and Tech. 2011; 3(4): 204-207.


Recomonded Articles:

Author(s): Leena Sahu, Amit Roy, Trilochan Satapathy

DOI:         Access: Open Access Read More

Author(s): Ravi Natvarlal Patel, Urviben Yashodharbhai Patel , Dhrubo Jyoti Sen

DOI:         Access: Open Access Read More

Author(s): Njoku, Obioma U., Joshua, Parker Elijah, Okonkwo, Chukwudi C.

DOI:         Access: Open Access Read More

Author(s): Manmohan S. Jangdey, Anshita Gupta, Abhishek K. Sah, Sanjay J. Daharwal

DOI:         Access: Open Access Read More

Author(s): B. Sehgal, G.B.Kunde

DOI:         Access: Open Access Read More

Author(s): Avani H. Sheth, Dhrubo Jyoti Sen, Naman B. Doshi

DOI:         Access: Open Access Read More

Author(s): Sherendra K. Sahu, R. R. Dwivedi, Skand K. Mishra, Neeta Singh, Sunita Gupta

DOI:         Access: Open Access Read More

Author(s): Salomi S., Muthukumaran P., Umamaheshwari R.

DOI:         Access: Open Access Read More

Author(s): Oula Alzeina, Lina soubh

DOI: 10.5958/2349-2988.2019.00026.3         Access: Closed Access Read More

Author(s): Nirjala Laxmi Madhikarmi, Kora Rudraiah Siddalinga Murthy

DOI:         Access: Open Access Read More

Research Journal of Science and Technology (RJST) is an international, peer-reviewed journal, devoted to science and technology...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2349-2988 


Recent Articles




Tags