Author(s):
D B Thorat, P S Rao, D H Nandal, Rahul Kunkulol
Email(s):
dattatraya_thorat@rediffmail.com
DOI:
10.5958/2349-2988.2021.00002.4 
Address:
D B Thorat1, P S Rao2, D H Nandal3, Rahul Kunkulol3
1PRES, Institute of Pharmacy, Loni, Tal - Rahata, Dist - Ahmednagar.
2Pravara Rural College of Pharmacy, Loni, Tal - Rahata, Dist - Ahmednagar.
3Pravara Institute of Medical Sciences (Deemed University), Loni, Tal - Rahata, Dist - Ahmednagar.
*Corresponding Author
Published In:
Volume - 13,
Issue - 1,
Year - 2021
ABSTRACT:
The phytochemical analysis of Hibiscus cannabinus showed the presence of phytosterols, flavonoids, polyphenols, tannins, steroids, alkaloids, saponins, lignans, essential oils, glucosides such as cannabiscitrin, cannabiscetin and anthocyanin glycoside. The pharmacological studies revealed that Hibiscus cannabinus possessed cytotoxic, anthelmintic, antibacterial, antiulcer, antidiabetic, hypolipidemic, antioxidant, immunological, haematinic and hepatoprotective effects. This review will highlight the chemical constituents, pharmacological and therapeutic properties of Hibiscus cannabinus.
Cite this article:
D B Thorat, P S Rao, D H Nandal, Rahul Kunkulol. A Review on Chemical constituents and Pharmacological properties of Hibiscus cannabinus leaves. Research J. Science and Tech. 2021; 13(1):8-12. doi: 10.5958/2349-2988.2021.00002.4
Cite(Electronic):
D B Thorat, P S Rao, D H Nandal, Rahul Kunkulol. A Review on Chemical constituents and Pharmacological properties of Hibiscus cannabinus leaves. Research J. Science and Tech. 2021; 13(1):8-12. doi: 10.5958/2349-2988.2021.00002.4 Available on: https://rjstonline.com/AbstractView.aspx?PID=2021-13-1-2
REFERENCE:
1. Al-Snafi AE. Pharmacological and therapeutic effects of Jasminum sambac- A review. Indo Am J P Sc 2018; 5[3]: 1766-1778.
2. Al-Snafi AE. Medical importance of Juniperus communis - A review. Indo Am J P Sc 2018; 5[3]: 1979-1792.
3. Al-Snafi AE. Pharmacological and therapeutic importance of Echium italicum- A review. Indo Am J P Sci 2017; 4[2]: 394-398.
4. Al-Snafi AE. Therapeutic importance of Ephedra alata and Ephedra foliata- A review. Indo Am J P Sci 2017; 4[2]: 399-406.
5. Al-Snafi AE. Chemical constituents and medical importance of Galium aparine - A review. Indo Am J P Sc 2018; 5[3]: 1739-1744.
6. Al-Snafi AE. The pharmacological effects of Helianthus annuus- A review. Indo Am J P Sc 2018; 5[3]:1745-1756.
7. Al-Snafi AE. Chemical constituents and pharmacological effects of Hypericum triquetrifolium. Indo Am J P Sc 2018; 5[3]: 1757-1765.
8. Al-Snafi AE. Therapeutic potential of Erodium cicutarium - A review. Indo Am J P Sci 2017; 4[2]: 407-413.
9. Al-Snafi AE. Chemical constituents and pharmacological effects of Fraxinus ornus- A review. Indo Am J P Sc 2018; 5[3]: 1721-1727.
10. Al-Snafi AE. Fumaria parviflora- A review. Indo Am J P Sc 2018; 5[3]: 1728-1738.
11. The plant list, a working list of all plant species, Hibiscus cannabinus, http://www.theplantlist. org/tpl1.1/record/kew-2849657
12. ITIS, Hibiscus cannabinus, https://www.itis.gov/servlet/SingleRpt/SingleRpt? Search topic=TSN & search value=21623#null
13. U.S. National Plant Germplasm System Taxon: Hibiscus cannabinus L., https://npgsweb.arsgrin.gov/gringlobal/taxonomydetail.aspx?19012
14. Liu AM. World production and potential utilization of jute, kenaf and allied fibers. In: Proceeding of the 2000 International Kenaf Symposium. Hiroshima- Japan 2000: 30-35.
15. Webber CL, Bhardwaj HL and Bledsoe VK. Kenaf production: fiber, feed, and seed. In : Trends in new crops and new uses. [ eds]: J Janick and A Whipkey. ASHS Press, Alexandria, VA 2002.
16. PROTA4U, Hibiscus cannabinus, /www.prota4u.org/database/protav8.asp?g pe&p=Hibiscus+cannabinus+L.
17. Kumar TR, Kumar EU, Sekar M and Kumar MKS. Antidiabetic activity of methanolic extract of Hibiscus cannabinus in streptozotocin induced diabetic rats. International Journal of Pharma and Bio Sciences 2011; 2[1]: P125-P130.
18. Duke JA. Handbook of energy crops 1983.
19. Lawton BP. Hibiscus. Timber Press, Cambridge, UK, 2004.
20. Agbor GA, Oben JE, Ngogang JY. Haematinic activity of Hibiscus cannabinus. African Journal of Biotechnology 2005; 4[8]: 833–837.
21. Lee YG, Byeon SE, Kim JY, Lee JY, Rhee MH, Hong S, Wu JC, Lee HS, Kim MJ, Cho DH and Cho JY. Immunomodulatory effect of Hibiscus cannabinus extract on macrophage functions. J Ethnopharmacol 2007;113[1]:62-71.
22. Moujir L, Seca AML, Silva AMS, López MR, Padilla N, Cavaleiro JAS and Neto CP. Cytotoxic activity of lignans from Hibiscus cannabinus. Fitoterapia 2007; 78: 385–387.
23. Nilugal KC, Fattepur S, Kazi HA, Bacayo MF, Asmani MF and Chittur AI. In vitro screening of Hibiscus cannabinus L. leaves extracts for antibacterial activity. World Journal of Pharmaceutical Research 2016; 5[6]: 369-378.
24. Mahadevan SN and Kamboj P. Antihyperlipidemic effect of hydroalcoholic extract of Kenaf [Hibiscus cannabinus L.] leaves in high fat diet fed rats. Annals of Biological Research 2010; 1[3]: 174-181.
25. Babita G, Arunbala A, Rashmi P, Chetan KD. Review on ethanopharmacological study of Hibiscus cannabinus. Int J Pharm Res Scholar 2014; 3[1]: 442-447.
26. Mozaina K, Mario RT, Charles LW, Franck ED, Kevin KS and David EW. Phytotoxic and fungitoxic activities of the essential oil of kenaf [Hibiscus cannabinus L.] leaves and its composition. J Agri Food Chem 2001; 49[8]: 3768-3771.
27. Kubmarawa D, Andenyang IFH and Magomya AM. Proximate composition and amino acid profile of two non-conventional leafy vegetables [Hibiscus cannabinus and Haematostaphis barteri]. African Journal of Food Science 2009; 3[9]: 233-236.
28. Mohamed A, Bhardwaj H, Hamama A and Webber C. Chemical composition of kenaf [Hibiscus cannabinus L.] seed oil. Industrial Crops and Products 1995; 4[3]: 157-165.
29. Seca AML, Silva AMS, Silvestre AJD, Cavaleiro JAS, Domingues FMJ and Neto CP. Chemical composition of the light petroleum extract of Hibiscus cannabinus bark and core Phytochemical Analysis 2000; 11[6]: 345–350.
30. Raju M, Varakumar S, Lakshminarayana R and Baskaran V. Carotenoid composition and vitamin A activity of medicinally important green leafy vegetables. Food Chemistry 2007; 101[4]: 1598-1605
31. Neto CP, Seca A, Fradinho D, Coimbra MA, Evtuguin D, Silvestre A and Cavaleiro JAS. Chemical composition and structural features of the macromolecular components of Hibiscus cannabinus grown in Portugal. Industrial Crops and Products 1996; 5[3]: 189-196.
32. Abd Ghafar SA, Ismail M, Yazan LS, Fakurazi S, Ismail N, Chan KW and Tahir P. Cytotoxic activity of kenaf seed oils from supercritical carbon dioxide fluid extraction towards human colorectal cancer [HT29] cell lines. Corporation Evidence-Based Complementary and Alternative Medicine 2013, http://dx.doi.org/ 10.1155/ 2013/ 549705
33. Sravanthi KC, Sarvani M and Srilakshmi S. Anthelmintic activity of Hibiscus cannabinus leaf extract. International Journal of Research in Ayurveda and Pharmacy 2011; 2[1]: 244-246.
34. Karthik S, Thirupathamma AL and Nagendhiran A. Evaluation of antimicrobial activity and synthesis of silver nanoparticles from Hibiscus cannabinus and Punica granatum. Journal of Nano Science and Nano Technology 2014; 2[4]:448-458.
35. Nyam KL, Tang JLK and Long K. Anti-ulcer activity of Hibiscus cannabinus and Hibiscus sabdariffa seeds in ulcer-induced rats. International Food Research Journal 2016; 23[3]:1164-1172.
36. Mukherjee S, Jagtap SD, Kuvalekar AA et al. Demonstration of the potential of Hibiscus cannabinus Linn. Flowers to manage oxidative stress, bone related disorders and free-radical induced DNA damage. Indian Journal of Natural Products and Resources 2010; 1[3]:322-327.
37. Agbor GA, Oben JE, Nkegoum B, Takala JP and Ngogang JY. Hepatoprotective activity of Hibiscus cannabinus [Linn.] against carbon tetrachloride and paracetamol induced liver damage in rats. Pakistan Journal of Biological Sciences 2005; 8[10]: 1397-1401.
38. Agbor GA, Oben JE, Brahim BO and Ngogang JY. Toxicity study of Hibiscus cannabinus. J Cameroon Academy of Sci 2004; 4[1]: 27-32.