Author(s): Dron P. Modi, Dhrubo Jyoti Sen

Email(s): dronmodi9110@gmail.com , dhrubosen69@yahoo.com

DOI: Not Available

Address: Dron P. Modi1 and Dhrubo Jyoti Sen2
1Department of Pharmaceutics, Arihant School of Pharmacy and Bio-Research Institute, Gandhinagar-382421, Gujarat, India
2Department of Pharmaceutical Chemistry, Shri Sarvajanik Pharmacy College, Gujarat Technological University, Arvind Baug, Mehsana-384001, Gujarat, India
*Corresponding Author

Published In:   Volume - 6,      Issue - 1,     Year - 2014


ABSTRACT:
Taste refers to a perception arising from the stimulation of taste buds present on the surface of the tongue. Humans can distinguish among five components of taste: sourness, saltiness, sweetness, bitterness, and umami (savory). Taste is an important parameter in case of drugs administering orally and is a critical factor to be considered while formulating orodispersible, melt in mouth, buccal tablet and other formulations which comes in contact with taste buds. Bitter and unpalatable taste is a major problem of certain drugs in formulations. Masking the bitter taste of drugs is a potential tool for the improvement of patient compliance which in turn decides the commercial success of the product. According to the year 2003 survey of pediatricians by the American Association of Pediatrics, unpleasant taste was the biggest barrier for completing treatment in pediatrics. The field of taste masking of active pharmaceutical ingredients (API) has been continuously evolving with varied technologies and new excipients. Two approaches are commonly utilized to overcome the bad taste of the drug. The first includes reduction of drug solubility in the saliva and second approach is to alter the ability of the drug to interact with taste receptor. Various methods are available to mask the undesirable taste of the drugs. Some of them are coating of drug particles, by formation of inclusion complexes, molecular complexes of drugs with other chemicals, solid dispersions, melting method, micro encapsulation, prodrugs, mass extrusion methods and ion exchange resins.


Cite this article:
Dron P. Modi, Dhrubo Jyoti Sen. Novel Electronic Taste Detector for Taste Masked Bitter Drugs: Emerging Approach to E-Taster . Research J. Science and Tech. 6(1): Jan.-Mar. 2014; Page 34-41.


Recomonded Articles:

Author(s): Ravi Kumar, Swati Patil, MB Patil, Mahesh S Paschapur, Sachin R Patil

DOI:         Access: Open Access Read More

Author(s): Debjit Bhowmik, K.P. Sampath Kumar, Lokesh Deb

DOI: 10.5958/2349-2988.2016.00012.7         Access: Closed Access Read More

Author(s): Bhushan A. Bhairav, Prajakta A. Kokane, Ravindra B. Saudagar

DOI: 10.5958/2349-2988.2016.00022.X         Access: Closed Access Read More

Author(s): RS Jadhav, PN Kendre, MH Kolhe, S N Lateef, SM Shelke, RK Godge

DOI:         Access: Open Access Read More

Author(s): Nikam Pooja, Baokar Shrikrishna, Undare Santosh, Patil R.N

DOI: 10.5958/2349-2988.2016.00001.2         Access: Open Access Read More

Author(s): Yatri R. Shah, Parimal M. Prajapati, Ravi N. Patel, Urvi Y. Patel, Dhrubo Jyoti Sen

DOI:         Access: Open Access Read More

Author(s): Priyanka Pandey, Rakesh Mehta, Ravi Upadhyay

DOI:         Access: Open Access Read More

Author(s): Mukesh K. Nag, Satish Patel, Shikha Shrivastava, S.J. Daharwal, Manju R. Singh, Deependra Singh

DOI:         Access: Open Access Read More

Author(s): Smita Kolhe, Dhananjay More

DOI:         Access: Open Access Read More

Author(s): B. Kalyana Ramu, M. Syam Bab, U. Viplava Prasad, P. Konda Babu

DOI: 10.5958/2349-2988.2019.00012.3         Access: Closed Access Read More

Author(s): Hiren M. Marvaniya, Divyesh J. Vanparia, Renu Chauhan, Dhrubo Jyoti Sen

DOI:         Access: Open Access Read More

Author(s): IKEWUCHI Catherine C, IKEWUCHI Jude C, ONYEIKE Eugene N., AYALOGU Edward O.

DOI:         Access: Open Access Read More

Author(s): Atul R. Bendale, Sachin B. Narkhede, Anil G. Jadhav, G. Vidyasagar

DOI:         Access: Open Access Read More

Author(s): Panchawat S.

DOI:         Access: Open Access Read More

Research Journal of Science and Technology (RJST) is an international, peer-reviewed journal, devoted to science and technology...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2349-2988 


Recent Articles




Tags