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Research Journal of Science and Technology
ISSN: 2349-2988(Online), 0975-4393(Print)
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Analytical Method Development and Validation of Ritonavir: A Review
R. K. Godge
S. D. Magar
Dipak Nalawade*, Dr. R. K. Godge, S. D. Magar
Pravara Rural College of Pharmacy, Pravaranagar.
Ritonavir is an anti-retroviral drug used in the treatment of HIV/ AIDS. Many times, Ritonavir is used alone and in combination with many anti-retroviral drugs. So far, around seventy nine analytical methods have been reported for various studies on analysis of Ritonavir in bulk, pharmaceutical formulations and biological fluids. Aim: To abbreviate the various analytical techniques such as Chromatography, Spectrophotometry; Capillary electrophoresis for estimation of Ritonavir. Method: This article deals with the study of the various type of analytical techniques such as Chromatography, Spectrophotometry; Capillary electrophoresis and also other techniques such as LC- MS/MS, and their applicability in analysis of Ritonavir. These techniques are either explored for the quantification, detection of metabolite and also for stability-studies of the Ritonavir.
Ritonavir, RP-HPLC, Validation.
Dipak Nalawade, R. K. Godge, S. D. Magar. Analytical Method Development and Validation of Ritonavir: A Review. Research J. Science and Tech. 2020; 12(2): 157-162.
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