Author(s):
Abhishek. B. Wakade, Shital. T. Waghmode, Omkar. A. Wagh, Uniket. M. Gosavi
Email(s):
wakadeabhishek45@gmail.com
DOI:
10.52711/2349-2988.2025.00007 
Address:
Abhishek. B. Wakade1, Shital. T. Waghmode2, Omkar. A. Wagh3, Uniket. M. Gosavi4
1-3Student, JBVP Vidyaniketan Collage of Pharmacy, Lakhewadi.
4Assistant Professor, Dept. of Pharmaceutical Quality Assurance, JBVP Vidyaniketan Collage of Pharmacy, Lakhewadi.
*Corresponding Author
Published In:
Volume - 17,
Issue - 1,
Year - 2025
ABSTRACT:
In the primary healthcare system, traditional medicinal herbs have long been utilized to treat a variety of illnesses. Shigru, or Moringa oleifera, is a multifunctional, drought-resistant tree that is mostly indigenous to India and is widely distributed in the northern sub-Himalayan parts of the country. In line with Ayurveda Shigru differs from other plants in that it possesses both the virya Pradhan and the rasa Pradhan qualities found in Aushadi and Ahariya dravyas. Its nutritional value is great and its therapeutic uses are amazing. An antioxidant herb is moringa. Nature has given us access to an extensive library of cures for all human maladies. Man has grown herbs for medical purposes in addition to food crops since the beginning of civilization. Because of man's natural curiosity, the knowledge of pharmaceuticals has grown over thousands of years, providing us with several efficient ways to provide health care today. The multipurpose tree Moringa pterygosperma Gaertn has social, medical, and nutritional benefits and is farmed and utilized in many nations worldwide. In Senegal In Benin, health services provide powdered Moringa pterygosperma Gaertn to treat children with mild malnutrition. It shown that local populations used Moringa pterygosperma Gaertn for therapeutic purposes. Kindom is a plant that has a wealth of chemical compounds, fake medications, and conventional medicines that might be used to build innovative treatments. The varied spectrum of bioactive chemicals found in Moringa oleifera, including antioxidants, anti-inflammatory agents, and antibacterial substances, are known to have therapeutic promise in the management of several health disorders, including as infections, diabetes, and cardiovascular diseases. Numerous pharmacological potential and health advantages, such as antibacterial, anticancer, antidiabetic, antioxidant, antihypertensive, anti-inflammatory, and cardioprotective qualities, have been demonstrated for M. oleifera seeds.
Cite this article:
Abhishek. B. Wakade, Shital. T. Waghmode, Omkar. A. Wagh, Uniket. M. Gosavi. A Review Article on Moringa oleifera. Research Journal of Science and Technology. 2025; 17(1):48-8. doi: 10.52711/2349-2988.2025.00007
Cite(Electronic):
Abhishek. B. Wakade, Shital. T. Waghmode, Omkar. A. Wagh, Uniket. M. Gosavi. A Review Article on Moringa oleifera. Research Journal of Science and Technology. 2025; 17(1):48-8. doi: 10.52711/2349-2988.2025.00007 Available on: https://rjstonline.com/AbstractView.aspx?PID=2025-17-1-7
REFERENCE:
1. Milind P, Nitin B. Harmless of Herbal Remedies. Antiseptic. 2005; 12(2): 532
2. Patil, MB, Jalalpure SS. Anti-inflammatory activity of leaves of Anacardium Occidentals Linn. Ind. J. Pharma. Sci. 2003; 6(1): 70-72.
3. J. W. Fahey. Trees for Life Journal. 2005; 1(5): 1–24.
4. J. O. Popoola, O. O. Obembe. J. Ethnopharmacol. 2013; 150: 682–691.
5. B. Sivasankari, M. Anandharaj, P. Gunasekaran. J. Ethnopharmacol. 2014; 153: 408–423.
6. F. Anwar, S. Latif, M. Ashraf, A. H. Gilani. Phytother. Res. 2007; 21: 17–25.
7. R. Abe, K. Ohtani. J. Ethnopharmacol. 2013; 145: 554–565.
8. J. E. Yabesh, S. Prabhu, S. Vijayakumar. J. Ethnopharmacol. 2014; 154: 774–789.
9. J. N. Kasolo, G. S. Bimenya, L. Ojok, J. Ochieng, J. W. Ogwal-Okeng. J. Med. Plant Res. 2010; 4: 753–757
10. R. Saini, K. Nandini, P. Shetty, P. Giridhar. Eur. Food Res. Tech., 2014, 238(6), 971-978.
11. M. G. Rajanandh, J. Kavitha. Int. J. Pharm. Tech. Res. 2010; 2(2): 1409-1414.
12. M. Mbailao, T. Mianpereum, N. Albert. J. Food Resource Sci. 2014; 3:12-20.
13. C. Y. Ragasa, R. M. Levida, M. J. Don, C.C. Shen, Philipp. Sci. Lett. 2012; 5(1): 46-52.
14. A. Leone, A. Spada, A. Battezzati, A. Schiraldi, J. Aristil, S. Bertoli. Int. J. Mol. Sci. 2015; 16: 12791-12835
15. Mehta, J., Shukla, A., Bukhariya, V., Charde, M. The magic remedy of Moringa oleifera: an overview. Int. J. Biomed. Adv. Res. 2011; 2: 215–227.
16. Jung, I.L. Soluble extract from Moringa oleifera leaves with a new anticancer activity. PLoS One. 2014; 9 (4): e95492.
17. Isitua, C.C., Ibeh, I.N. Toxicological assessment of aqueous extract of Moringa oleifera and Caulis bambusae leaves in rabbits. J. Clin. Toxicol. 2013; S12, 003.
18. Asiedu-Gyekye, I.J., Frimpong-Manso, S., Awortwe, C., Antwi, D.A., Nyarko, A.K. Micro- and macro elemental composition and safety evaluation of the nutraceutical Moringa oleifera leaves. J. Toxicol. 2014; 786979: 1–13.
19. Gupta, S., Jain, R., Kachhwaha, S., Kothari, S.L. Nutritional and medicinal applications of Moringa oleifera Lam. Review of Current Status and future possibilities. J. Herb Med. 2018; 11: 1–11.
20. Radovich T, Farm and forestry production and marketing profile for Moringa oleifera
21. Ram P, Mehrotra BN, Compendium of Indian Medicinal Plants. Vol. I, Central Drug Research Institute Luhnow and National Institute of Science Communication, New Delhi. 2001, 280
22. Hassan FAG, Ibrahim MA. Moringa oleifera: Nature is Most Nutritious and Multi Purpose Tree. International Journal of Scientific and Research Publications. 2013; 3(4): 1-5.
23. Fahey JW. Moringa oleifera: A Review of the Medical Evidence for Its Nutritional, Therapeutic, and Prophylactic Properties. Part 1. Trees for Life Journal. 2005; 1:5.
24. Singh L, Jyoti and Singh J. Medicinal and Nutritional Values of Drumstick Tree (Moringa oleifera) – A Review. International Journal of Current Microbiology Applied. Science. 2019; 8(5):1965-1974.
25. Sodhi G, Das S, Mazumder A and Rana SK. Ethnopharmacological Review of Drum Stick (Moringa oleifera): Prevalently Used As An Alternative Medicine. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2019; 10(3): 458-468
26. Sahay S, Yadav U, Srinivasamurthy S. Potential of Moringa oleifera as a functional food ingredient: A review. International Journal of Food Science and Nutrition. 2017; 2 (5): 31-37.
27. Ram P, Rastogi, Mehrotra BN, Compendium of Indian Medicinal Plants. Vol. IV, Central Drug Research institute Luhnow and National Institute of Science Communication, New Delhi, 2001; 85-89.
28. Foid N, Makkar HPS, Becker K (2001) The potential use of Moringa oleifera for agriculture and Industrial uses. In: the Miracle tree, CTA, USA. 230-233.
29. Morton JF. The horseradish tree Moringa pterygosperma A boon toarid. land Econ. Bot. 1991; 45: 318-333.
30. Sachan A, Meena AK, Kaur R, Pal B, Singh B. Moringa pterygosperma A Review. J. Pharm. Res. 2010; 3: 840-482.
31. Burkill JH, A Dictionary of Economic Product of the Malay peninsula, Vol. 2. Art Printing Work Publishers, Kuala Lumpur, Malaysia, 1966, 315-317.
32. Akhouri S, Prasad A and Ganguly S. Moringa oleifera Leaf Extract Imposes Better Feed Utilization in Broiler Chicks. Journal of Biology and Chemical Research. 2013; 30(2): 447-450.
33. Faizi S, Siddiqui BS, Saleem R, Siddiqui S, Aftab K, Gilani AH. Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry. 1995; 38: 957-963.
34. Murakami A, Kitazono Y, Jiwajinda S, Koshimizu K, Ohigashi H. Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirements for inhibition of tumor- promotor- induced Epstein-Barr virus activation. Planta Medica. 1998; 64: 319-323.
35. Chumark P, Khunawat P, Sanvarinda Y and Phornchirasilp S. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. Leaves. Journal of Ethnopharmacology. 2008; 116(3): 439-46
36. Ghasi S, Nwobodo EO, Ezekwesili- Ofili JO. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats. Journal of Ethnophramacology. 2000; 69(1): 21-5.
37. Anwar F, Latif S, Ashraf M and Gilani AH. Moringa oleifera: A Food Plant with Multiple Medicinal Uses. Phytotherapy Research. 2007; 21: 17–25.
38. Havsteen BH. The biochemistry and medical significance of the flavonoids. Pharmacology and Therapeutics. 2002; 96: 67–202.
39. Middleton Jr., E.; Kandaswami, C.; Theoharides, T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacological Reviews. 2000; 52: 673–751
40. Miean HK, Mohamed S. Flavonoid (Myricetin, Quercetin, Kaempferol, Luteolin, and Apigenin) Content of Edible Topical Plants. Journal of Agricultural and Food Chemistry. 2001; 49: 3106-3112
41. J. Xie, L. J. Peng, M. R. Yang, W. W. Jiang, J. Y. Mao, C. Y. Shi, Y. Tian and J. Sheng, J. Evidence-Based Complementary Altern. Med. 2021; 2021: 5591687.
42. M. J. Tuorkey, Interv. Med. Appl. Sci. 2016; 8: 109–117.
43. F. Wang, S. Long and J. Zhang, Arch. Oral Biol. 2021; 132: 105280.
44. T. P. Omayone, O. M. Ijomone, S. B. Oloyede, S. T. Okunola, Z. O. Aigoro, V. U. Esukpa and S. O. Dinakin, J. Basic Clin. Physiol. Pharmacol. 2021, DOI: 10.1515/jbcpp-20210149,000010151520210149.
45. I. A. Adebayo, H. Arsad, N. N. S. b. N. M. Kamal and M. R. Samian, S. Afr. J. Bot. 2020; 129: 379–387.
46. Esther O, Oladipo A. Preliminary test of phytochemical screening of crude extracts of Moringa oleifera Seed. J Appl Chem. 2012; 3(2): 11–13.
47. Sinha S. Phytochemical analysis and antibacterial potential of Moringa oleifera Lam. Int J Sci Innovations Discoveries. 2012; 2(4): 401–407
48. Idris MA, Jami MS, Hammed AM, et al. Moringa oleifera seed extract: a review on its environmental applications. Int J Appl Environ Sci. 2016; 11(6): 1469–1486.
49. Leone A, Spada A, Battezzati A, et al. Cultivation,genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview. Int J Mol Sci. 2015; 16(6): 12791–12835.
50. Oluduro OA, Aderiye BI, Connolly JD, et al.Characterization and antimicrobial Activity of 4-(b-D-glucopyranosyl-1!4-a-L-rhamnopyranosyloxy)-benzyl thiocarboxamide; a novel bioactive compound from Moringa oleifera seed extract. Folia Microbiol. 2010; 55(5): 422–426.
51. Mehta S, Rai PK, Rai NK, et al. Role of spectral studies in detection of antibacterial phytoelements and phytochemicals of Moringa oleifera. Food Biophys. 2011; 6(4): 497–502.
52. Oliveira JT, Silveira SB, Vasconcelos IM, Cavada BS, Moreira RA. Compositional and nutritional attributes of seeds from the multipurpose tree Moringa oleifera Lamarck. J Sci Food Agric 1999; 79: 815-20.
53. The Wealth of India (A Dictionary of Indian Raw Materials and Industrial Products). Raw Materials. New Delhi: Council of Scientific and Industrial Research; 1962. p. 425-9.
54. Ndabigengesere A, Narasiah KS. Quality of water treated by coagulation using Moringa oleifera seeds. Water Res. 1998; 32: 781-91.
55. Asiedu-Gyekye IJ, Frimpong-Manso S, Awortwe C, Antwi DA, Nyarko AK. Micro-and macroelemental composition and safety evaluation of the nutraceutical Moringa oleifera leaves. J Toxicol. 2014; 2014: 1-13.
56. Fatima N, Fatima JS. Pharmacological screening for anti-arthritic activity of Moringa oleifera. Asian J Pharm Clin Res 2016; 9: 106-11.
57. Bukar A, Uba A and Oyeyi TI. Antimicrobal profile of Moringa oleifera Lam. Extracts against some food- borne microorganisms. Bayero Journal of Pure and Applied Sciences. 2010; 3(1): 43 -48.
58. Renitta RE, Anitha J and Napolean P. Isolation, analysis and identification of phytochemicals of antimicrobial activity of Moringa oleifera Lam. Current Biotica. 2009; 3(1): 33-37.
59. Doughari JH, Pukuma MS, De N. Antibacterial effects of Balanites aegyptiaca L. Drel. And Moringa oleifera Lam. on Salmonella typhi. African Journal of Biotechnology. 2007; 6(19): 2212- 2215
60. Dewangan G, Koley KM, Vadlamudi VP, Mishra A, Poddar A and Hirpurkar SD. Antibacterial activity of Moringa oleifera (drumstick) root bark. Journal of Chemical and Pharmaceutical Research. 2010; 2(6): 424-428.
61. Jabeen R, Shahid M, Jamil A and Ashraf M. Microscopic evaluation of the antimicrobial activity of seed extracts of Moringa oleifera. 2008; 40(4): 1349-1358.
62. Pal SK, Mukherjee PK, Saha K, Pal M and Saha BP. Antimicrobial actions of the leaf extract of Moringa oleifera LAM. Ancient Science of Life. 1995; 15(3): 197 – 199.
63. Devaraj VC, Asad M and Prasad S. Effect of leaves and fruits of Moringa oleifera on gastric and duodenal ulcers. Pharmaceutical Biotechnology. 2007; 45: 332-338.
64. Devaraj VC, Gopala Krishna B. Antiulcer activity of a polyherbal formulation (PHP) from Indian medicinal plants. Chinese Journal of Natural Medicines. 2013; 11(2): 145-148
65. Guevara AP, Vargas C, Sakurai H, Fujiwara Y, Hashimoto K, Maoka T, et al. An antitumor promoter from Moringa oleifera lam. Mutat Res 1999; 440: 181-8.
66. Divi SM, Bellamkonda R, Dasireddy SK. Evaluation of antidiabetic and anti-hyperlipedemic potential of aqueous extract of Moringa oleifera in fructose fed insulin resistant and STZ induced diabetic wistar rats: A comparative study. Asian J Pharm Clin Res. 2012; 5: 67-72.
67. AI-Malki AL, El Rabey HA. The antidiabetic effect of low doses of Moringa oleifera lam. Seeds on streptozotocin induced diabetes and diabetic nephropathy in male rats. Biomed Res Int. 2015; 2015: 381040.
68. Rajendran S, Saravanan R, Ramalingam S, Hameed SA. Antiproliferative and antioxidant activity of Gynandropsis pentaphylla Linn on MCF-7 cell line. Int J Pharm PharmSci. 2014; 6: 561-5
69. Tiloke C, Phulukdaree A, Chuturgoon AA. The antiproliferative effect of Moringa oleifera crude aqueous leaf extract on cancerous human alveolar epithelial cells. BMC Complement Altern Med. 2013; 13: 226.
70. Jung IL. Soluble extract from Moringa oleifera leaves with a new anticancer activity. PLoS One. 2014; 9: e95492.
71. .Leelawat S, Leelawat K. Moringa oleifera extracts induce cholangio carcinoma cell apoptosis by induction of reactive oxygen species production. Int J Pharm Phytochem Res. 2014; 6: 183-9.
72. Sutar NG, Bonde CG, Patil VV, Narkhede SB, Patil AP, Kakade RT. Analgesic activity of seeds of Moringa oleifera Lam. Int J Green Pharm. 2008; 2: 108-10.
73. Agrawal B, Mehta A. Anti-asthmatic activity of Moringa oleifera Lam: A clinical study. Ind J Pharm. 2008; 40: 28-31.
74. Bais S, Singh GS, Sharma R. Anti-obesity and hypolipidemic activity of Moringa oleifera Leaves against high fat diet-induced obesity in rats. Adv Biol. 2014; 2014: 9
75. Giri IC, Shamim QM, Khan S, Patel J, Choudhary R, Singh A. Evaluation of the anthelmintic activity of Moringa oleifera seeds. Int J Pharm Prof Res. 2010; 1: 1
76. Gilani AH, Aftab K, Suria A, Siddiqui A, Salem R, Siddiqui BS, et al. A pharmacological study on hypotensive and spasmodic activities of pure compounds from Moringa oleifera. Phyto Res. 1994; 8: 87-91.
77. Dangi SY, Jolly CI, Narayana S. Antihypertensive activity of the total alkaloids from the leaves of Moringa oleifera. Pharm Biol. 2002; 40: 144-8
78. Caceres A, Saravia A, Rizzo S, Zabala L, DeLeon E, Nave F. Pharmacologic properties of Moringa oleifera. 2: Screening for antispasmodic, anti-inflammatory and diuretic activity. J Ethnopharm. 1992; 36: 233-7.
79. Ruckmani K, Kavimani S, Anandan R, Jaykar B. Effect of Moringa oleifera Lam on paracetamol- induced hepatotoxicity. Ind J Pharm Sci. 1998; 60: 33-5.
80. Stohs S.J., Hartman M.J. Review of the Safety and Efficacy of Moringa oleifera. Phytother. Res. 2015; 29: 796–804. doi: 10.1002/ptr.5325.
81. Aekthammarat D., Pannangpetch P., Tangsucharit P. Moringa oleifera leaf extract lowers high blood pressure by alleviating vascular dysfunction and decreasing oxidative stress in L-NAME hypertensive rats. Phytomedicine. 2019; 54: 9–16. doi: 10.1016/j.phymed.2018.10.023.
82. Tahkur R.S., Soren G., Pathapati R.M., Buchineni M. Diuretic activity of Moringa oleifera leaves extract in swiss albino rats. J. Pharm. Innov. 2016; 5: 8–10.
83. Bhat S.K., Joy A.E. Antianxiety effect of ethanolic extract of leaves of Moringa oleifera in Swiss albino mice. Arch. Med. Health Sci. 2014; 2: 5–7.
84. Misra A., Srivastava S., Srivastava M. Evaluation of antidiarrheal potential of Moringa oleifera (Lam.) leaves. J. Pharmacogn. Phytochem. 2014; 2: 43–46.
85. Zhang Y., Peng L., Li W., Dai T., Nie L., Xie J., Ai Y., Li L., Tian Y., Sheng J. Polyphenol Extract of Moringa oleifera Leaves Alleviates Colonic Inflammation in Dextran Sulfate Sodium-Treated Mice. Evid. Based Complement. Altern. Med. 2020; 2020: 6295402. doi: 10.1155/2020/6295402.
86. Woldeyohannes M.G., Eshete G.T., Abiye A.A., Hailu A.E., Huluka S.A., Tadesse W.T. Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice. Biochem. Res. Int. 2022; 2022: 2090–2247. doi: 10.1155/2022/5768805.
87. Posmontier B. The medicinal qualities of Moringa oleifera. Holist. Nurs. Pr. 2011; 25: 80–87. doi: 10.1097/HNP.0b013e31820dbb27.
88. Gopalakrishnan L., Doriya K., Kumar D.S. Moringa oleifera: A review on nutritive importance and its medicinal application. Food Sci. Hum. Wellness. 2016; 5: 49–56. doi: 10.1016/j.fshw.2016.04.001.
89. Karadi R.V., Gadge N.B., Alagawadi K.R., Savadi R.V. Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats. J. Ethnopharmacol. 2006; 105: 306–311. doi: 10.1016/j.jep.2005.11.004.
90. Debnath S., Guha D. Role of Moringa oleifera on enterochromaffin cell count and serotonin content of experimental ulcer model. Indian J. Exp. Biol. 2007; 45: 726–731.
91. Paliwal R., Sharma V., Pracheta A Review on Horse Radish Tree (Moringa oleifera): A Multipurpose Tree with High Economic and Commercial Importance. Asian J. Biotechnol. 2011; 3: 317–328. doi: 10.3923/ajbkr.2011.317.328
92. Ghasi S., Nwobodo E., Ofili J.O. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed wistar rats. J. Ethnopharmacol. 2000; 69: 21–25. doi: 10.1016/S0378-8741(99)00106-3.
93. Rathi B.S., Bodhankar S.L., Baheti A.M. Evaluation of aqueous leaves extract of Moringa oleifera Linn for wound healing in albino rats. Indian J. Exp. Biol. 2006; 44: 898–901.
94. Bhattacharya A., Tiwari P., Sahu P.K., Kumar S. A review of the phytochemical and pharmacological characteristics of Moringa oleifera. J. Pharm. Bioallied Sci. 2018; 10: 181–191.
95. Pandey A., Pandey R.D., Tripathi P., Gupta P.P., Haider J., Bhatt S., Singh A.V. Moringa oleifera Lam. (Sahijan)—A plant with a plethora of diverse therapeutic benefits: An Updated Retrospection. Int. J. Med. Aromat. 2012; 1: 1–8. doi: 10.4172/2167-0412.1000101.
96. Meireles D., Gomes J., Lopes L. A review of properties, nutritional and pharmaceutical applications of Moringa oleifera: Integrative approach on conventional and traditional Asian medicine. Adv. Tradit. Med. 2020;20:495–515. doi: 10.1007/s13596-020-00468-0.
97. Liu W.L., Wu B.F., Shang J.H., Wang X.F., Zhao Y.L., Huang A.X. Moringa oleifera seed ethanol extract and its active component kaempferol potentiate pentobarbital-induced sleeping behaviours in mice via a GABAergic mechanism. Pharm. Biol. 2022; 60: 810–824. doi: 10.1080/13880209.2022.2056207.
98. Gothai S., Arulselvan P., Tan W.S., Fakurazi S. Wound healing properties of ethyl acetate fraction of Moringa oleifera in normal human dermal fibroblasts. J. Intercult. Ethnopharmacol. 2016; 5: 1–6. doi: 10.5455/jice.20160201055629.
99. Toma A., Deyno S. Phytochemistry and pharmacological activities of Moringa oleifera. Indian, J. Pharmacol. 2014; 4: 222–231.
100. Guevara AP, Vargas C, Sakurai H, Fujiwara Y, Hashimoto K, Maoka T, et al. An antitumor promoter from Moringa oleifera lam. Mutat Res 1999; 440: 181-8.
101. Kerharo PJ. Un remede populaire sengalais: Le ‘Nebreday’ (Moringa oleifera lann.) employs therapeutique sen milieu Africain chimieet pharmacologie. Plantes Med Phytother 1969; 3: 14-219.
102. Kurma SR, Mishra SH. Anti-inflammatory and hepato-protective activities of fruits of Moringa pterygosperma Gaertn. Ind J Nat Pro. 1998a; 14: 3-10.
103. Kurma SR, Mishra SH. Hepatoprotective principles from stem bark of Moringa pterygosperma. Pharm Biol. 1998b; 36: 295-300.
104. Tahiliani P, Kar A. Achyranthes aspera elevates thyroid hormone levels and decreases hepatic lipid peroxidation in male rats. J Ethnopharmacol 2000; 71: 527-32.
105. Siddhuraju P, Becker K. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera lam.) leaves. J Agric Food Chem. 2003; 51: 2144-55.
106. Hartwell JL. Medicinal Characteristic of Moringa oleifera Leaves and Seeds. Ohio, New York: McGraw Hill Company; 1967.
107. Dahot MU. Vitamin contents of flowers and seeds of Moringa oleifera. Pak J Biochem Mol Biol. 1988; 21: 1-24.
108. Abdull Razis AF, Ibrahim MD, Kntayya SB. Health benefits of Moringa oleifera. Asian Pac J Cancer Prev APJCP. 2014;15(20):8571-8576.
109. Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S. Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview. Int J Mol Sci. 2015; 16(6): 12791-12835.
110. Stohs SJ, Hartman MJ. Review of the safety and efficacy of Moringa oleifera. Phytother Res. 2015; 29(6): 796-804.
111. Chen C, Zhang B, Huang Q, Fu X, Liu RH. Microwave-assisted extraction of polysaccharides from Moringa oleifera Lam. leaves: characterization and hypoglycemic activity. Ind Crops Prod. 2017; 100(supplement C): 1-11.
112. Agrawal B, Mehta A. Antiasthmatic activity of Moringa oleifera Lam: A clinical study. Indian J Pharmacol. 2008; 40(1): 28-31.
113. Iwu MM. Handbook of African medicinal plants, second edition. CRC Press; 2014. 508 p.
114. Mootoosamy A, Fawzi Mahomoodally M. Ethno-medicinal application of native remedies used against diabetes and related complications in Mauritius. J Ethnopharmacol. 2014; 151(1): 413-444.
115. Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-okeng JW. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J Med Plants Res. 2010; 4(9): 753-757.
116. Die`ye AM, Sarr A, Diop SN, et al. Medicinal plants and the treatment of diabetes in Senegal: survey with patients. Fundam Clin Pharmacol. 2008; 22(2): 211-216.
117. Monera T, Maponga C. Moringa oleifera supplementation by patients on antiretroviral therapy. J Int AIDS Soc. 2010; 13(4): P188
118. Sivasankari B, Anandharaj M, Gunasekaran P. An ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of Thoppampatti, Dindigul district, Tamilnadu. India. J Ethnopharmacol. 2014; 153(2): 408-423=
119. Yabesh JEM, Prabhu S, Vijayakumar S. An ethnobotanical study of medicinal plants used by traditional healers in silent valley of Kerala, India. J Ethnopharmacol. 2014;154(3):774-789.
120. M. Poussel, E. Penven, C. Richard, S. Jacquenet, F. Chabot, and C. Paris. Occupational asthma to ‘the miracle tree’ (Moringa oleifera): First description. J. Allergy Clin. Immunol. Pract. 2015; 3(5): 813–814 doi: 10.1016/j.jaip.2015.05.016.
121. L. J. Berglund. Anaphylaxis to Moringa oleifera First description. Australas. Med. J. 2018; 11(3); 176–177 doi: 10.21767/amj.2018.3344.
122. F. O. Olanrewaju, O. Onayemi, O. A. Olasode, and M. M. Oripelaye. Fixed drug eruption induced by moringa oleifera leaf extracts – A case report. Our Dermatology Online. 2017; 8(4): 413–416 doi: 10.7241/ourd.20174.117.
123. H. Adégbidi et al. Fixed Pigmented Erythema Induced. Clin. Res. Dermatology. 2019; 2(2): 1–3.
124. E. W. R. A. Witharana, W. M. G. A. S. T. B. Wijetunga, and S. K. J. Wijesinghe. Stevens Johnson syndrome (SJS) following Murunga leaf (Moringa oleifera) consumption. Ceylon Med. J. 2018; 63(4): 188 doi: 10.4038/cmj.v63i4.8771.
125. A. Sagrera, T. Montenegro, and L. Borrego. Cutaneous Toxicity Due to Moringa oleifera. Actas Dermo-Sifiliográficas (English Ed.). 2021; 112(10): 953–954 doi: 10.1016/j.adengl.2021.09.008.
126. M. S. Deogade, V. Kumbhare, and S. Gaidhane. Moringa oleifera Lam. Enriched Biscuits Induced Adverse Drug Reaction- a Case Report. 2019; 16(2): 27–30.
127. A. Acharya, L. Freeman, and M. R. Alvarez. A Case of Necrotizing Myopathy After Moringa Use. 2020.
128. Treidler et al. Necrotizing myopathy in two patients after the use of Moringa (P2.137). Neurology. 2017; 88(16): P2.137, 2017. http://n.neurology.org/content/88/16_Supplement/P 2.137.abstract.